Feature Based Analysis of MSVM on Brain MRI Images

Abstract

Multiclass Support Vector Machine (MSVM) is a multi-class classifier is used to solve real life health problems of human beings mostly in Alzheimer’s disease (AD) diagnosis. MSVM able to deal efficiently multi class classification problems in Medical diagnosis. MSVM are successfully applied in the fields of Text categorization, Handwriting Recognition, Protein Structure Prediction, etc.Various Magnetic Resonance Image (MRI) features are used to get accurate diagnosis of AD as it is safe, reliable and noninvasive. Biomarkers are quantifiable indicatorsforspecific disease state or anotherphysicalstate of an organism. At early stage of AD diagnosis biomarkers are usedand they are also used to get objective and reliable measures of disease diagnosis. A few biomarkers can be used to diagnose AD like MRI scan, PET Scan, SPECT Scan, etc., Among these, two biomarkers namely Morphometric features and Texture features are chosen for this study.To perform quantitativeassessments and to identify the important changes in the brainmorphometric analysis is consider as a primary tool. Hippocampus is one among the key biomarkers to know about the state and progression in AD.Texture analysis is a model that permits mathematical identification of changes in MRI there byquantitative and reproducible strategy for extracting image features. Two feature based models are proposed using MSVM to classify the MRI Images. The performance of proposed models is analyze and the best model is evaluated.