Optimization and Analysis of Micro Needle

Abstract

The principle that involves the disruption of skin with microneedle is that it  creates a path of micron size  which is used to deliver the drug directly into the epidermis or the upper layer of dermis without any interrupt. Though it overcome the problems of hypodermic needle it has some limitations. Many researches done on the microneedle and increased the length of the needle to deliver the drug more deeper into the skin, but it results in the buckling and stress which may cause damage to the cells or tissues. So it is very important to consider the geometrical parameters like length, diameter and material property of the microneedle to overcome those limitations of mechanical stability of the needle  and efficient  drug delivery. This review guides you to know about the various microneedle with different parameters and different materials(PMMA,Silicon) and their results of stress which helps in choosing the better  microneedle for delivering the drug without any damages of tissues and effective delivery.